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Whilst very low-depend MBL not often progresses to CLL, significant-rely MBL progresses to CLL necessitating therapy at a price of 1% to 2% each year. High-rely MBL is distinguished from Rai 0 CLL dependant on whether the B-cell depend is earlier mentioned or underneath 5 × 109/L. Despite the fact that men and women with equally large-count MBL an